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Product Code: EMS3750

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Bringing Correlative light and electron microscopy forward with the CryoCapsule

High pressure freezing is the most advanced technology when it comes to vitrify a hydrated biological specimen while preserving the ultrastructure. Developed in the 80's [1], the technology evolved progressively to become accessible to a larger community. Still, the sample preparation prior to HPF remains tedious and often comes to advance expertise depending on the specimen [2].

The CryoCapsule is a new tool in the field of High Pressure Freezing (HPF) and correlative light and electron microscopy (CLEM). Comparable to a small petri dish, it is composed of a landmarked sapphire disc and a gold spacer ring (50Micrometre thick) maintained together by a plastic ring [3].


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