Ultra Small Immuno Gold nanoparticles

Aurion Ultra Small Immunogold Reagents are prepared with sub nanometer gold particles. These particles have far less influence on the adsorbed antibodies or detecting molecules, and consequently the conjugates behave as though they are uncoupled. In conjunction with the highly efficient and easy-to-use R-Gent SE-LM and SE-EM silver enhancement reagents, the Ultra Small Immunogold Reagents are the best choice for any application.

Reduction of the gold particle size provides Ultra Small Immunogold Reagents with fundamentally different characteristics when compared with conjugates built around larger particles. While the Conventional Immunogold Reagents can be thought of as particles coated with proteins, Ultra Small Immunogold Reagents are proteins coated with one or more gold particles. With this structure, both the overall size of the conjugates, as well as steric hindrance are decreased.

The table below lists a few physical characteristics of gold conjugates.

Particle
diameter
#Au
atoms
MWt.
(daltons)
#particles
/ml
#Ab
/(part.)
0.8nm 15 3·10^3 5·10^15 0.1-1?
6nm 6500 1.3·10^6 2.4·10^13 1-2
10nm 30·10^3 6·10^6 5·10^12 7-12

Specificity:

Aurion offers the widest range of Ultra Small Immunogold Reagents. The most used reagent types are available as intact IgG, F(ab’)2 and Single Fab conjugates. Ultra Small Immunogold Reagents are prepared using the highest quality antibodies or binding agents available. All antibodies are immuno affinity purified and immuno cross-adsorbed to reduce non-specific interactions.

Storage:

Ultra Small Immunogold Reagents have a guaranteed shelf life of 18 months from the date of quality control analysis. The products should be stored at 4-8°C. Freezing is not recommended.

 

CHEM Ultra Small Immuno Gold Reagents

 

 

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