Methanol for chromatography, ACS grade (DG)
Methanol for chromatography, ACS grade (DG)
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LiChrosolv solvents exhibit high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations. Intended for HPLC and UHPLC-MS applications.
Featured in method development of:
- Benazepril - USP Method Benazepril RS
- Betamethasone - USP Method Betamethasone Valerate Assay
- Irbesartan - USP Method Irbesartan Assay
- Lamivudine - USP Method Lamivudine RS
- Lansoprazole - USP Method Lansoprazole RS
- Levofloxacin - USP Method Levofloxacin RS - USP Method Levofloxacin Assay
- Nifedipine - USP Method Nifedipine RS - USP Method Nifedipine Assay
- Pharmacopoeia Monograph Methods - HPLC and UHPLC methods for Regulated Drug Analysis
- Pioglitazone - USP Method Pioglitazone HCl RS - USP Method Pioglitazone HCl Assay
Features:
- suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
- specified quality in positive and negative in positive and negative electrospray ionisation (ESI) and atmospheric-pressure chemical ionisation-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)
—ESI/APCI (+) < 2ppb
—ESI/APCI (-) < 10ppb - lowest impurity profile: for interference-free baselines (test 2)
- microfiltered through 0.2 μm filter (test 3) to provide:
—A long lifespan to filters and mechanical parts of HPLC systems
––reduced risk of column clogging - packaged in borosilicate glass bottles for minimised metal ion contaminations
- lowest levels of trace metal impurities for a minimum metal ion adduct formation
—<5ppb - lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)
Preparation Note: Product filtered through a 0.2μm filter
Analysis Note:
Evaporation Number: 1.9
Purity (GC): ≥99.8%
Identity (IR): conforms
Evaporation residue: ≤3.0mg/l
Water: ≤0.03%
Colour: ≤10 Hazen
Acidity: ≤0.0002meq/g
Alkalinity: ≤0.0002meq/g
Transmission (at 225nm): ≥50%
Transmission (at 240nm): ≥80%
Transmission (from 265nm): ≥98%
Filtered by 0.2µm filter
HPLC grade
Vapor density: 1.11 (vs air)
Vapor pressure: 128hPa (20°C), 410mmHg (50°C), 97.68mmHg (20°C)
Isocratic
Autoignition temp: 385°C
Potency: 5628mg/kg LD50, oral (Rat), 17100 mg/kg LD50, skin (Rabbit)
Expl. limit: 36%
Evaporation residue: ≤3.0mg/L
Refractive index: n20/D 1.329 (lit.)
Kinematic viscosity: 0.54-0.59 cSt (20°C)
Boiling point: 64.7°C (lit.)
Melting point: −98°C (lit.)
Flash point: 9.7°C
Density: 0.791g/mL at 25°C (lit.)
Storage temperature: 2-30°C
Images are illustrative only. Please check product details before ordering.